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SETSCI - Volume 4 (6) (2019)
ISAS WINTER-2019 (ENS) - 4th International Symposium on Innovative Approaches in Engineering and Natural Sciences, Samsun, Turkey, Nov 22, 2019

Inhibition and Antimicrobial Activity of Lavandula stoechas Essential Oil on Escherichia coli, Staphylococcus aureus and Candida albicans
Yusuf Sıcak1*, Elif Ayşe Erdogan Eliuz2, Eyüp Başaran3, Hatice Ulusoy4
1Muğla Sıtkı Koçman University, Muğla, Turkey
2Mersin University, Mersin, Turkey
3Batman University, Batman, Turkey
4Muğla Sıtkı Koçman University, Muğla, Turkey
* Corresponding author:
Published Date: 2019-12-22   |   Page (s): 485-489   |    193     8

ABSTRACT In the present study, the volatile compounds of essential oil of Lavandula stoechas L. (Lavender) was analysed by gas chromatography-mass spectrometry (GC-MS) using the Nist and Willey libraries. It was determined that the main components of L. stoechas were linalyl acetate (36.31%) and linalool (34.18%). Inhibition and antimicrobial activity of volatile oil of the plant against Escherichia coli (ATCC 25293), Staphylococcus aureus (ATCC25925) and Candida albicans were examined by microbroth dilution method. L. stoechas EO (Essential Oil) exhibited antimicrobial activity with MIC of between 14.8 and 32.5 µg/mL. The lowest antimicrobial activity were determined against E. coli in L. stoechas EO (MIC= 32.5 µg/mL), while maximum MIC were noticed as 14.8 µg/mL against C. albicans. The most cell inhibition were noted as 91.76% in C. albicans at the concentration of 4500 µg/mL of L. stoechas. The reductions in living cell number were obtain as 0.54 log in E. coli, 1.04 log in S. aureus and 1.08 log in C. albicans at the same concentration of 4.5 µg/mL. This study showed the strong antimicrobial performance of L. stoechas EO in detail. This study showed that L. stoechas EO inhibits the growth of microorganisms depending on concentration.  
KEYWORDS Lavandula stoechas, antimicrobial action, cell inhibition, reduction of living cell
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