Open Access

Mechanical and Solubility Behavior of Chitosan Coated Hydroxyapatite Foams

Rasul    Dadaev1*, Mevlüt    Gürbüz2
1Ondokuz Mayıs University, Samsun  , Turkey  
2Ondokuz Mayıs University, Samsun  , Turkey  
* Corresponding author: dadaevrasul9@gmail.com

Presented at the 3rd International Symposium on Innovative Approaches in Scientific Studies (Engineering and Natural Sciences) (ISAS2019-ENS), Ankara, Turkey, Apr 19, 2019

SETSCI Conference Proceedings, 2019, 4, Page (s): 632-633

Published Date: 01 June 2019

In this study highly porous hydroxyapatite foam fabricated by powder metallurgy method for various sintering temperatures and coated with chitosan after sintering. The solubility of the samples were in Lactated Ringer's solutions for various day. From the results compression strength developed from ⁓1.2 MPa to ⁓12 MPa. The pH of the solution was changed from ⁓7 to 7.45 and 7.28 for uncoated and chitosan coated samples. Finally, the sintered samples at 1150 oC for 2h showed the highest density and compressive strength.  

Keywords - Hydroxyapatite, chitosan, foam, compression, solubility

[1] A. Pasinli, R. S. Aksoy, Yapay Kemik Uygulamaları İçin Hidroksiapatit. Electronic Journal of BioTechnology.Vol: 1, No: 1, (41-51), 2010

[2] S.J. Kalita, A. Bhardwaj and H.A. Bhatt, Nanocrystalline calcium phosphate ceramics in biomedical engineering. Materials Science Engineering C 27, 441–449. (2007).

[3]Z. Evis., Çeşitli İyonlar Eklenmiş Nano-Hidroksiapatitler: Üretim Yöntemleri, İç Yapı, Mekanik ve Biyouyumluluk Özellikleri Yönlerinden İncelenmesi. International Journal of Research and Development, Vol.3, No.1, (55-61) January 2011

[4] D.W. Hutmacher, Scaffolds in tissue engineering bone and cartilage, Biomaterials, 21, 2529-43, 2000.

[5] B. Mavis, T.T. Demirtas, M. Gumusderelioglu, G. Gunduz, U. Colak, Synthesis, characterization and osteoblastic activity of polycaprolactone nanofibers coated
with biomimetic calcium phosphate, Acta Biomaterialia, 5, 3098-111, 2009.

[6] S.F. Hulbert, F.A. Young, R.S. Mathews, J.J. Klawitter, C.D. Talbert, F.H. Stelling, Potential of ceramic materials as permanently implantable skeletal prostheses, Journal of Biomedical Materials Research, 4, 433-56, 1970.

[7] V. Karageorgiou, D. Kaplan, Porosity of 3D biomaterial scaffolds and osteogenesis, Biomaterials, 26, 5474-91, 2005.

[8]S.Çakmak,Kemik Doku Onarimi için Hidroksiapatit/Peptit Amfifil Bazli Nanokompozit Doku İskelelerinin Geliştirilmesi, Hacettepe Üniversitesi. Doktora Tezi, 2015

[9] R. Dadaev and M. Gürbüz, Optimization of Process Prarameters for Porous Artificial Bone, International Journal of Multidisciplinary Studies and Innovative Technologies, Volume : 3 Number: 1 Year: 2019 Pages: 28-30

0
Citations (Crossref)
316
Total Views
23
Total Downloads

Licence Creative Commons This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
SETSCI 2025
info@set-science.com
Copyright © 2025 SETECH
Tokat Technology Development Zone Gaziosmanpaşa University Taşlıçiftlik Campus, 60240 TOKAT-TÜRKİYE