Presented at the 3rd International Symposium on Innovative Approaches in Scientific Studies (Social, Human and Administrative Sciences) (ISAS2019-SHAS), Ankara, Turkey, Apr 19, 2019

SETSCI Conference Proceedings, 2019, 5, Page (s): 48-54 , https://doi.org/

Published Date: 02 June 2019    | 710     19

Uyku bozuklukları toplumda yaygın olarak görülen bir halk sağlığı sorunudur. Uyku; zaman, ışık, beslenme gibi birçok çevresel faktörden etkilenen 24 saatte bir tekrar eden sirkadiyen ritmin önemli bir parçasıdır. Uyku bozuklukları; İnsomnia [kronik uykusuzluk], Obstrüktif Uyku Apnesi [OUA] ve Vardiyalı Çalışma Sendromu olarak sınıflandırılmaktadır. Obstrüktif uyku apnesi ve kronik uykusuzluk gibi çeşitli uyku bozuklukları, birçok sağlık problemleri ve bozulmuş yaşam kalitesi ile ilişkilendirilmektedir. Kronik uykusuzluk kortizol seviyesi ve sempatik sinir sistemi belirteçlerinde artma, bağışıklık sistem belirteçlerinde azalma gibi birçok hormonal ve metabolik değişiklikler ile ilişkilidir. Obsrüktif Uyku Apnesi ise neden olduğu hipoksik stres ve uyarılar ile; endotel disfonksiyonu, hipertansiyon, artmış arteriyel sertlik ve ateroskleroz ile ilişkili hormonal ve metabolik anormallikleri tetiklemektedir. Uyku bozuklukları neden olduğu bu hormonal ve metabolik değişikliklerle obezite, insülin direnci, diyabet, hipertansiyon ve kardiyovasküler hastalık gelişimiyle ilişkilendirilmiştir. Son yıllarda yapılan çalışmalarda kardiyovasküler hastalıkların uyku bozukluklarına neden olabileceği öne sürülmektedir.

Keywords - Uyku bozuklukları, obstrüktif uyku apnesi, obezite, kardiyovasküler hastalıklar

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