{
    "article_id": 795,
    "public_id": "f9ba7823-5dd2-411f-bb69-18e99ec55bb8",
    "internal_identifier": null,
    "source_identifier": "39:160",
    "status": "published",
    "type": "research_article",
    "title": "Laurus nobilis L. Uçucu Yağının Sekiz Farklı Klinik İzolata Karşı Antibakteriyal Aktivitesinin Araştırılması",
    "title_secondary": null,
    "abstract": "Bu çalışmada Laurus nobilis L. türüne ait 5 farklı ticari uçucu yağın (T1, T2, T3, T4 ve T5), 8 farklı klinik izolata karşı\r\nantimikrobiyal aktivitesi araştırılmıştır. Bu amaçla antimikrobiyal aktivite deneylerinde disk difüzyon ve mikrodilüsyon\r\nyöntemleri kullanılmıştır. Tüm klinik izolatlara karşı antimikrobiyal aktiviteye sahip olan uçucu yağların Minimum İnhibitör\r\nKonsantrasyonu (MİK) belirlenmiştir. Araştırmada en yüksek inhibisyon zon çapları T1, T2, T3 ve T5 ticari uçucu yağlarından\r\nelde edilmiş ve sırasıyla Klebsiella pneumaniae klinik izolatı için 31,00 mm, Bacillus cereus klinik izolatı 1 için 12,00 mm,\r\nEscherichia coli klinik izolatı için 37,75 mm ve yine Escherichia coli klinik izolatı için 47,75 mm olarak belirlenmiştir.\r\nÇalışmada en düşük inhibisyon zon çapları, T1 ve T5 ticari uçucu yağılarından Serratia marcescens klinik izolatı için sırasıyla\r\n10,00 mm ve 07,00 mm olarak belirlenmiştir.\r\nAraştırmada denenen MİK konsantrasyon aralığı %8 ile %0,0625 değerleri arasında olmuştur. Tüm klinik izolatlara karşı etkili\r\nbulunan T3 ve T5 ticari uçucu yağlarından elde edilen MİK değerleri %0,0125 ile %8 arasında tespit edilmiştir. Araştırmanın\r\nbundan sonraki aşamalarında klinik izolatlara karşı etkili bulunan ticari uçucu yağların GC-MS analizlerinin yapılması ve\r\nelektron mikroskobu ile hücreler üzerine etkinliğin tespit edilmesi planlanmaktadır.  ",
    "language": "tr",
    "english_title": "Investigation of Antibacterial Activity of Laurus nobilis L. Essential Oil against Eight Different Clinical Isolates",
    "english_abstract": "In this study, antimicrobial activity of 5 different commercial essential oils (T1, T2, T3, T4 and T5) belonging to Laurus nobilis L. species against 8 different clinical isolates were investigated. For this purpose, disc diffusion and microdilution methods were used in antimicrobial activity experiments. Minimal Inhibitor Concentration (MIC) of essential oils having antimicrobial activity against all clinical isolates was determined. The highest inhibition zone diameters were obtained from T1, T2, T3 and T5 commercial essential oils and 31,00 mm for Klebsiella pneumaniae clinical isolate, 12,00 mm for Bacillus cereus clinical isolate 1, 37,75 mm for Escherichia coli and 47,75 mm for Escherichia coli clinical isolate. The lowest inhibition zone diameters were determined as 10,00 and 07,00 mm for Serratia marcescens clinical isolates from T1 and T5 commercial essential oils, respectively. The range of MIC concentrations tested in the study was between 8% and 0,0625%. MIC values obtained from T3 and T5 commercial essential oils which are effective against all clinical isolates were determined between 0,0125% and 8%. In the next stages of the study, it is planned to make GC-MS analysis of commercial essential oils which are effective against clinical isolates and to determine the activity on the cells by electron microscopy.",
    "doi": null,
    "doi_url": null,
    "resource_url": "https://www.set-science.com/a/f9ba7823-5dd2-411f-bb69-18e99ec55bb8",
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    "authors": [
        {
            "public_id": "a14e7009-9728-4e36-9968-a6e4e39a0d1f",
            "given": "Binnur",
            "family": "Meriçli Yapıcı",
            "full": "Binnur Meriçli Yapıcı",
            "literal": null,
            "orcid": null,
            "orcid_url": null,
            "email": "byapici@comu.edu.tr",
            "corresponding": true,
            "sequence": "first",
            "affiliations": [
                {
                    "name": "Çanakkale Onsekiz Mart University",
                    "department": null,
                    "country": null,
                    "country_code": null,
                    "ror": null,
                    "ror_url": null
                }
            ]
        },
        {
            "public_id": "a3951178-2ce4-49a1-8c34-22348d4ffc93",
            "given": "Ayşen",
            "family": "Kaya",
            "full": "Ayşen Kaya",
            "literal": null,
            "orcid": null,
            "orcid_url": null,
            "email": "byapici@comu.edu.tr",
            "corresponding": false,
            "sequence": "additional",
            "affiliations": [
                {
                    "name": "Çanakkale Onsekiz Mart University",
                    "department": null,
                    "country": null,
                    "country_code": null,
                    "ror": null,
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    "keywords": [],
    "translations": [
        {
            "language": "en",
            "title": "Investigation of Antibacterial Activity of Laurus nobilis L. Essential Oil against Eight Different Clinical Isolates",
            "abstract": "In this study, antimicrobial activity of 5 different commercial essential oils (T1, T2, T3, T4 and T5) belonging to Laurus nobilis L. species against 8 different clinical isolates were investigated. For this purpose, disc diffusion and microdilution methods were used in antimicrobial activity experiments. Minimal Inhibitor Concentration (MIC) of essential oils having antimicrobial activity against all clinical isolates was determined. The highest inhibition zone diameters were obtained from T1, T2, T3 and T5 commercial essential oils and 31,00 mm for Klebsiella pneumaniae clinical isolate, 12,00 mm for Bacillus cereus clinical isolate 1, 37,75 mm for Escherichia coli and 47,75 mm for Escherichia coli clinical isolate. The lowest inhibition zone diameters were determined as 10,00 and 07,00 mm for Serratia marcescens clinical isolates from T1 and T5 commercial essential oils, respectively. The range of MIC concentrations tested in the study was between 8% and 0,0625%. MIC values obtained from T3 and T5 commercial essential oils which are effective against all clinical isolates were determined between 0,0125% and 8%. In the next stages of the study, it is planned to make GC-MS analysis of commercial essential oils which are effective against clinical isolates and to determine the activity on the cells by electron microscopy.",
            "keywords": [
                "Defne, Esansiyel Yağ, Antimikrobiyal Aktivite, Klinik Bakteri, Minimum İnhibitör Konsantrasyonu"
            ]
        }
    ],
    "subjects": [],
    "subject_names": [],
    "published_date": "2018-12-31",
    "published_year": "2018",
    "received_date": null,
    "accepted_date": null,
    "volume": "3",
    "issue": null,
    "page_first": "848",
    "page_last": "852",
    "article_number": null,
    "conference": {
        "short_name": "ISAS2018-Winter",
        "full_title": "2nd International Symposium on Innovative Approaches in Scientific Studies",
        "name": "2nd International Symposium on Innovative Approaches in Scientific Studies",
        "acronym": "ISAS2018-Winter",
        "location": "Samsun, Türkiye",
        "start_date": "2018-11-30",
        "end_date": null,
        "public_id": "b8a703cc-09f7-4d5b-ae60-eb31a1050720"
    },
    "proceedings": {
        "title": "2nd International Symposium on Innovative Approaches in Scientific Studies",
        "series_title": "Setsci conference indexing system",
        "publisher": "SET Technology",
        "isbn": null,
        "eisbn": null,
        "issn": "2618-6446",
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        "doi": null,
        "doi_prefix": null,
        "slug": "setsci-volume-3-2018-legacy-39",
        "public_id": "641f522e-9cf0-4c89-be17-c6037f3d1bca",
        "url": "https://www.set-science.com/p/setsci-volume-3-2018-legacy-39"
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        "name": "CC BY 4.0",
        "url": "https://creativecommons.org/licenses/by/4.0/",
        "code": "CC-BY-4.0",
        "open_access": true
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    "copyright": {
        "holder": "SET Technology",
        "year": "2018"
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    "funding_statement": null,
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    "history": {
        "published": "2018-12-31"
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}